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Synthetic Phospholipids have greater procoagulant activity than phospholipids extracted from natural biological sources. They are useful in Non Activated Clotting Time (NAPTT) tests for activated clotting factors and procoagulants. Also for specifically bypassing the effect of lupus anticoagulants (LA) in phospholipid correction tests and as platelet lipid substitutes in APTT and dRVVT reagents. We guarantee a competitive price for our reagents.
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Code: X9113
Proportion of dioleyl phosphatidyl serine: dioleyl phosphatidyl choline (DOPS: DOPC) = 3:7. Much higher activity and better reproducibility than brain phospholipids.
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Code: X9115
DOPE:DOPS:DOPC= 5:3:2. Optimal phospholipid blend for coagulation.
1. Etscheid M, et. al. Identification of Kallikrein and FXIa as impurities in therapeutic immunoglobulins: implications for the safety and control of intravenous blood products. Vox Sang. 2012; 102 (1): 40-6
2. Exner T, Rickard, K.A, Kronenberg, H. Studies on phospholipids in the action of a lupus coagulation inhibitor. Pathology. 1975; 7 (4): 319-28
3. Zwaal R F, et. al. Lipid-protein interactions in blood coagulation. Biochim Biophys Acta. 1998;1376(3):433-53
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