SACT-II

Surface Activated Clotting Time - II
SACT-II is a simple, inexpensive screening method for the detection of circulating lupus anticoagulants.​
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Format:
liquid reagent
Status:
RUO
Product Code:
X9601
Size:
5 x 10mL
Storage:
2-8°C
Stability:
2 years

Product Features:

Sensitive test for Lupus Anticoagulant
Substitute for KCT or SCT

Product Description:

Surface Activated Clotting Time-II (SACT-II) reagent is a clear, stable, phospholipid-free suspension of an aluminosilicate mineral which activates contact factors similarly to kaolin or silica. The SACT-II reagent can thus be used as a substitute for kaolin suspension in kaolin clotting time (KCT) or silica clotting time tests as a screening test for LA, running in regular APTT mode on automated clotting instruments. Abnormal results need to be followed up mixing tests with normal plasma, use of HRRS (if heparin is suspected) and factor assays.

We guarantee a competitive price for our reagents.

IFU - ARTG Listed (Australia)IFU - Antihepca™-HRRS RUO (International)IFU - CE Marked (Europe)IFU - RUO (U.S.A.)
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References:

1. Exner T, Rickard KA, Kronenberg H. A sensitive test demonstrating lupus anticoagulant and its behavoural patterns. Brit J Haematol.1978;40;143-151.
2. Chantarangkul V, Tripodi A, Arbini KMA, Mannucci PM. Silica clotting time as a screening and confirmatory test for lupus anticoagulants. Thromb. Res. 1992; 67; 355-365.
3. Lesperance B, et al. Relative sensitivity of different tests in the detection of low titer lupus anticoagulants. Thromb Haemost. 1988; 60;217-9.
4. Galli M, Finazzi G, Bevers EM. Kaolin clotting time and dilute Russells viper venom time distinguish between prothrombin dependent and beta 2 glyco-protein I dependent antiphospholipid antibodies. Blood 1995; 86; 617-623.
5. Brandt JT, et al. Criteria for the diagnosis of lupus anticoagulants: An update. Thromb. Haemostas. 1995; 74;1185-1190.
6. Exner T, et. al. Effect of an activated charcoal product (DOAC STOPTM) intended for extracting DOAC on various other APTT-prolonging agents. Clin Chem Lab Med. 2019; 57; 690-696
7. Eby C. Antiphospholipid syndrome review. Clin. Lab Med. 2009; 29; 305-319.
8. Devreese K, Hoylaerts MF. Laboratory diagnosis of the antiphospholipid syndrome: a plethora of obstacles to overcome. European Journal of Haematology, 83: 1-16.

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